Found 19 matching trials
Study of GSK1120212 Plus Gemcitabine vs Placebo Plus Gemcitabine in Metastatic Pancreatic Cancer PHASE2 GSK1120212 is a potent and highly selective inhibitor of MEK phosphorylatio...
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GSK Investigational Site
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Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites PHASE2 This is a global, multi-centre, open-label, study of GSK2118436 conducted i...
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GSK Investigational Site
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Compassionate Use Program BRAF Mutation-positive Patients in the Adjuvant Treatment of Melanoma After Surgical Resection N/A The purpose of this Treatment Plan is to allow access to trametinib and dab...
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No Longer Available
Location
Multiple Locations
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Pharmacokinetics of Repeat Oral Doses of Dabrafenib and the Combination of Dabrafenib and Trametinib in Chinese Subjects With Melanoma PHASE1 Present clinical study will be conducted in China to evaluate the pharmacok...
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Multiple Locations
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Compassionate Use Program to Access Trametinib and Dabrafenib for Patients With BRAF Mutation-positive Metastatic Melanoma N/A The purpose of this Cohort Treatment Plan is to allow access to trametinib ...
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No Longer Available
Location
Multiple Locations
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GSK1120212 Food-effect Study PHASE1 The purpose of the this study is to evaluate the effect of a high-fat, high...
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GSK Investigational Site
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Dabrafenib With Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma (COMBI-AD). PHASE3 This was a two-arm, randomized, double-blind Phase III study of dabrafenib ...
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Novartis Investigative Site
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Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain PHASE2 This is a multi-cohort, open label, Phase II study with Dabrafenib (GSK2118...
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Novartis Investigative Site
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Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors PHASE2 The purpose of this study was to investigate the activity of dabrafenib in ...
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Children's Hospital of Orange County
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Access Study of Trametinib for Subjects With Advanced Unresectable (Stage IIIc) or Distant Metastatic (Stage IV) BRAF V600E/K Mutation Positive Cutaneous Melanoma N/A This is a single arm open label, multicenter, non randomized, access study ...
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No Longer Available
Location
GSK Investigational Site
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